In a world where Hunters and Witches have formed an alliance to protect humans from Rogues, Dean Winchester is a Master Hunter. The last of a long line of Hunters, Dean is on the trail of Azazel, one of the most powerful Rogues that has ever existed. Knowing that he can't Hunt the Rogue alone, Dean visits the city of Nouvelle Orleans and the High Witch who holds it. She offers him her heir, Samuel, and the two leave. In their search for Azazel, they find secrets buried beneath secrets and a stunning revelation that could change the entire world.

Tsuna is not quite human, neither are his guardians. Magic and flames can have some odd interactions.

He saw the horn poking out from the pony's head, golden and straight and somehow delicate-looking despite the empty tuna can hanging off of it. The unicorn horn. "The fuck," Sidney said out loud, his eye skipping from the horn over the greyish-white body to the graceful gold-toned hooves.